Dry eyes can make everyday life uncomfortable, causing irritation, redness, and blurred vision. One of the most effective natural ways to support eye health is through high quality fish oil supplements rich in omega 3 fatty acids.
These essential fats help reduce inflammation, improve tear production, and support overall eye moisture. With so many options available, choosing the right supplement can feel confusing. That is why we have carefully selected the top 10 best fish oil supplements for dry eyes relief.
This guide focuses on purity, potency, absorption, and user satisfaction to help you find a reliable option for long lasting eye comfort and better visual wellness.
10. Focus Omega 3 Dry Eye Relief Supplement
Focus Relief Plus Formula for Dry Eyes delivers a potent blend of re‑esterified triglyceride (rTG) omega‑3s, providing 1,620 mg of fish oil per serving with more than 90 % EPA and DHA.
Developed and recommended by eye doctors, this supplement also includes 75 mg of GLA to help maintain healthy tear production and support retinal health.
The high‑concentration omega‑3s are proven in recent studies to promote ocular surface stability, making them an ideal part of a routine for occasional dry‑eye symptoms.
Each dose comes in a soft‑gel that’s easy to swallow, and the suggested regimen is just three softgels taken once daily with a meal. Made in the USA at an NSF‑certified facility, Focus Relief Plus undergoes rigorous third‑party testing on every lot to ensure purity, potency, and patient safety.
Pros
- Clinically‑backed omega‑3 concentration for eyes
- Developed and endorsed by eye‑care professionals
- Supports retinal health and tear film stability
- Easy‑to‑swallow softgel, three‑a‑day dosing
- NSF‑certified, third‑party tested for safety
Cons
- Requires daily intake with meals
- May not suit vegans or fish‑allergy sufferers
- Softgels larger than typical capsules
9. Nature’s Bounty Triple Strength Omega 3 Softgels 2400mg
Triple Strength Omega‑3 Fish Oil delivers a powerhouse 2,400 mg of marine‑sourced EPA & DHA in every serving. Each bottle contains 180 burpless softgels flavored with natural lemon, making daily supplementation pleasant and easy.
The oil is sourced from wild‑caught, deep‑ocean fish, then molecularly distilled to remove heavy metals, PCBs, and other contaminants.
This ultra‑pure formula provides 864 mg EPA and 576 mg DHA per dose, supporting heart rhythm, joint flexibility, eye clarity, brain function, skin health, and even colon cleansing.
The enteric‑free softgels are coated to prevent fishy aftertaste, while the non‑GMO, gluten‑free, sugar‑free composition meets strict GMP standards in a USA‑based facility.
Third‑party testing guarantees potency and safety, giving you confidence in a clean, high‑potency supplement that’s suitable for both men and women.
Pros
- Triple‑strength 2,400 mg omega‑3 per serving
- Lemon‑flavored, burpless softgels eliminate aftertaste
- High EPA (864 mg) & DHA (576 mg) content
- Molecular distillation removes heavy metals & contaminants
- Non‑GMO, gluten‑free, sugar‑free, USA‑bottled
Cons
- Large softgel size may be difficult for some
- Daily dosage requires taking multiple capsules
- Premium price reflects high purity and potency
8. Macuhealth Omega 3 Softgels
Macuhealth Omega 3 Fish Oil delivers a powerhouse blend of marine‑derived nutrients designed to support eye and brain health.
Each serving packs 1,100 mg DHA and 1,100 mg EPA, plus an extra 250 mg of complementary omega‑3 fatty acids, giving you a total of 2,200 mg of omega‑3s per dose.
The softgels are formulated in a triglyceride base for superior absorption and feature a smooth coating that minimizes aftertaste, making daily supplementation effortless.
Premium fish oil is combined with antioxidant‑rich rosemary extract, sunflower oil, and natural tocopherols to protect the delicate oils from oxidation.
With flexible intake recommendations, you can tailor the dosage to your personal health goals while enjoying a convenient, high‑potency formula that fits seamlessly into any routine.
Pros
- Triple strength omega‑3 for eye health
- Smooth softgel reduces unpleasant aftertaste
- High potency 2,200 mg per serving
- Antioxidant blend preserves oil freshness
- Flexible dosing for individualized needs
Cons
- May cause mild fishy aftertaste for sensitive users
- Softgels larger than typical capsules
- Requires consistent daily intake for best results
7. Sports Research Omega-3 1250 Softgel Capsules
Sports Research® Omega‑3 Fish Oil 1250 delivers a triple‑strength, 10‑step molecular‑distilled oil that’s always fresh, never fishy.
Each softgel packs 1,250 mg of wild‑caught Alaska Pollock oil, providing a minimum of 1,040 mg of omega‑3s in the natural triglyceride form—690 mg EPA and 260 mg DHA.
Because the potency is so high, just one capsule a day meets the recommended EPA + DHA intake, eliminating the need for multiple doses.
The fish are harvested from the pristine Bering Sea, and the oil carries MSC certification and an IFOS 5‑Star rating, guaranteeing sustainable sourcing, traceability, and purity.
Manufactured in a U.S. cGMP‑compliant facility, the formula is Non‑GMO, pescatarian‑friendly, gluten‑free, hexane‑free, and third‑party tested for heavy metals, oxidation, and active potency.
Omega‑3 fatty acids support cardiovascular health, joint flexibility, and eye function, making this a powerful addition to any wellness routine. With rigorous testing and eco‑responsible sourcing, Sports Research offers a clean, potent supplement that works as hard as you do.
Pros
- Fresh, non‑fishy softgel every dose
- One‑a‑day convenience, high potency
- Sustainably sourced MSC‑certified Alaska pollock
- Triglyceride‑form EPA & DHA for better absorption
- Non‑GMO, gluten‑free, hexane‑free formula
Cons
- Slightly higher price than basic fish oils
- Requires consistent daily intake
- May have a mild aftertaste for sensitive users
6. Nature Made Burp Less Omega 3 Fish Oil
Nature Made Burp‑Less Ultra Omega‑3 delivers a potent 1,400 mg dose of purified fish oil in each softgel, designed for one‑a‑day convenience.
Each bottle contains 90 softgels—enough for a full three‑month supply—so you can keep your heart, brain, and eyes nourished without the dreaded fishy aftertaste.
The formula is refined to remove mercury and other contaminants, and the special “burp‑less” coating helps prevent the unpleasant reflux that many fish‑oil users experience.
With 683 mg EPA and 252 mg DHA per serving, this supplement supports cardiovascular health, cognitive function, and visual acuity.
It’s gluten‑free, dairy‑free, contains no added colors, and is free from shellfish, making it suitable for a wide range of dietary preferences. For optimal absorption, take the softgel with water and a meal.
As the #1 pharmacist‑recommended brand, Nature Made offers confidence in quality and purity, though the product is not intended to diagnose, treat, cure, or prevent any disease.
Pros
- Burp‑less coating eliminates fishy reflux
- High EPA/DHA concentration supports heart health
- Pure, mercury‑removed fish oil for safety
- Gluten‑ and dairy‑free, suitable for many diets
- One‑a‑day convenience for 90‑day supply
Cons
- May be pricey compared to generic brands
- Softgel size could be large for some users
- Requires meals for best absorption
5. ScienceBased Health HydroEye – 120 Softgels
ScienceBased Health HydroEye Dry Eye Supplement delivers a clinically‑tested, inside‑out approach to eye comfort.
Each softgel blends a precise ratio of gamma‑linolenic acid (GLA) from black‑currant seed oil, omega‑3 EPA & DHA, and supporting nutrients that together nurture all three layers of the tear film.
In a peer‑reviewed trial published in Cornea, the formula proved effective at promoting a healthy ocular surface and lasting relief. For optimal results, take four softgels daily and allow 30–60 days of consistent use; continued daily dosing maintains the benefits.
Key Features
– Works from the inside out to nourish the eye
– Clinically tested in a peer‑reviewed Cornea study
– Proprietary, balanced blend of GLA, EPA, DHA, and nutrients
– Unique GLA source from black‑currant seed oil (not in fish or flaxseed)
– Recommended dosage: four softgels daily, 30–60 days for full effect
Pros
- Supports all three tear‑film layers naturally
- Clinically validated eye‑comfort results
- Unique GLA source enhances dry‑eye relief
- Balanced omega‑3 blend promotes visual health
- Simple daily regimen, easy to remember
Cons
- Requires consistent daily intake for benefits
- May take up to two months to notice full effect
- Not suitable for those with fish/seafood allergies (contains omega‑3)
4. TheraTears Omega 3
TheraTears Omega 3 Supplement for Eye Care delivers a powerful blend of 1200 mg fish oil, organic flaxseed oil, and antioxidant‑rich vitamin E to nourish and protect your eyes.
Each serving supplies 450 mg EPA, 300 mg DHA, and 450 mg ALA—key omega‑3 fatty acids shown to improve tear‑film stability and reduce ocular irritation.
Developed by an ophthalmologist after 18 years of research, this clinically tested formula combines triglyceride‑rich fish oil with sustainably sourced flaxseed oil for optimal absorption.
The brand is doctor‑recommended (per ProVoice Survey 9/1/23‑8/31/24) and many plans allow FSA/HSA reimbursement, making premium eye‑care accessible.
Pros
- Supports eye comfort and visual clarity
- Clinically tested blend ensures reliable efficacy
- High EPA/DHA/ALA levels for comprehensive nutrition
- Ophthalmologist‑created, doctor‑recommended formula
- Vitamin E antioxidant protection enhances stability
Cons
- May cause mild fishy aftertaste
- Requires consistent daily intake for best results
- Not suitable for vegans due to fish oil
Give your eyes the balanced hydration they deserve with TheraTears Omega 3—your daily ally against dryness and fatigue.
3. Nature’s Bounty Omega-3 Fish Oil
Our De3 Dry Eye Ultra Pure rTG Omega‑3 delivers a potent 2,400 mg of EPA + DHA in a convenient 3‑softgel, 2‑month regimen.
The patented 3:1 EPA‑to‑DHA ratio works from within the tear glands to boost the quality of natural oil, easing grittiness, dryness, and burning without any fishy aftertaste.
Thanks to a refined distillation process, the oil is re‑esterified triglyceride (rTG) – the most bio‑available form of omega‑3, so your body absorbs it quickly and efficiently.
Take one softgel three times a day for 90 days and you’ll start to notice clearer, more comfortable eyes. Each batch is produced in an NSF‑certified, cGMP‑compliant facility in Norway, bottled, and third‑party tested in the USA.
Backed by the PVG (PRN Vision Group) line, more than 4,000 eye‑care professionals trust these fish‑oil capsules for their patients’ dry‑eye relief.
Pros
- Burpless formula eliminates fishy aftertaste completely
- High EPA/DHA concentration reaches optimal eye nutrition
- rTG form ensures superior absorption and effectiveness
- Clinically‑backed 90‑day protocol shows visible results
- Manufactured in NSF‑certified, cGMP‑compliant facility
Cons
- Requires three softgels per day
- Benefits may take up to 90 days to appear
- Not suitable for vegans or fish‑allergy sufferers
2. Thorne Research De3 2400mg EPA & DHA
Our De3 Dry Eye Ultra Pure rTG Omega‑3 delivers a potent blend of 2400 mg EPA + DHA in a burpless, easy‑to‑swallow softgel.
The patented 3:1 EPA‑to‑DHA ratio supports the tear‑gland’s natural oil production, helping to soothe gritty, dry or burning sensations within 90 days of consistent use.
Thanks to a rigorous molecular‑distillation process, the oil is re‑esterified triglyceride (rTG) – the form the body absorbs most efficiently – while removing unwanted toxins.
Just three softgels a day (morning or night) provide the optimal eye‑nutrition dose without the dreaded fishy aftertaste.
Manufactured in an NSF‑certified, cGMP‑compliant facility in Norway and third‑party tested in the USA, this supplement meets the high standards trusted by over 4,000 ophthalmologists and optometrists who recommend the PVG line for eye health.
Each bottle supplies a three‑month regimen, making it a convenient, long‑term solution for anyone seeking clearer, more comfortable vision.
Pros
- Burpless softgels, no fishy aftertaste
- High EPA:DHA (3:1) boosts tear‑film quality
- rTG form ensures superior absorption efficiency
- Clinically supported results in 90 days*
- NSF‑certified, cGMP‑compliant manufacturing standards
Cons
- Requires daily intake for best effect
- Three‑month supply may be pricey upfront
- Not suitable for vegans (fish‑derived)
1. Omega-3 De3 Dry Eye
De3 Dry Eye Ultra Pure rTG Omega‑3 delivers a powerful 2,400 mg blend of EPA and DHA in a burpless, easy‑to‑absorb form. Each daily dose of three softgels works to soothe gritty, dry, or burning sensations, helping your eyes feel refreshed without the typical fishy aftertaste.
The patented 3:1 EPA‑to‑DHA ratio supports the tear‑gland’s natural oil production, while a refined distillation process removes impurities and creates re‑esterified triglyceride (rTG) omega‑3 that the body can absorb more efficiently.
Manufactured in an NSF‑certified, cGMP‑compliant facility in Norway and third‑party tested in the USA, the formula meets strict quality standards.
As part of the PRN Vision Group (PVG) line, it’s doctor‑recommended by over 4,000 ophthalmologists and optometrists, offering a convenient, month‑long supply that can show noticeable results after about 90 days of consistent use.
Pros
- Burpless softgels eliminate fishy aftertaste
- High EPA/DHA concentration targets eye nutrition
- rTG form ensures superior absorption and efficacy
- Clinically backed 3:1 EPA‑to‑DHA ratio
- NSF‑certified, cGMP‑compliant manufacturing standards
Cons
- Requires three pills daily for full benefit
- May take up to 90 days to notice effects
- Not suitable for vegans or fish‑allergy sufferers
Frequently Asked Questions
What makes a fish oil supplement effective for relieving dry eyes?
- High EPA/DHA concentration: Look for products that provide at least 500 mg combined EPA and DHA per serving, as these omega‑3s support the tear film’s lipid layer.
- Molecularly‑distilled or purified: This reduces oxidation and removes contaminants (e.g., mercury, PCBs).
- Triglyceride or re‑esterified form: These are better absorbed than ethyl‑ester oils, ensuring more EPA/DHA reaches ocular tissues.
- Added antioxidants (e.g., vitamin E): They help prevent the oil from becoming rancid, preserving potency.
How many fish oil capsules should I take daily to see improvement in dry‑eye symptoms?
- Typical dose: 1,000 – 2,000 mg of combined EPA + DHA per day (often 2–4 softgels, depending on the product).
- Start low: Begin with the manufacturer’s recommended serving and gradually increase if tolerated.
- Consistency matters: Benefits usually appear after 4–8 weeks of regular use, so take the supplement daily rather than intermittently.
- Consult your eye‑care professional: They can tailor the dose to your specific condition and any other medications you’re using.
Are there any safety concerns or interactions when using fish oil for dry eyes?
- Bleeding risk: High doses (≥3 g/day) may prolong bleeding time, especially if you’re on anticoagulants (warfarin, clopidogrel) or aspirin.
- Allergies: Choose a fish‑oil product that’s molecularly distilled to minimize fish‑protein residues if you have a seafood allergy.
- Digestive upset: Taking capsules with meals, preferably a larger one containing fat, reduces fishy aftertaste and stomach discomfort.
Conclusion
Choosing the right fish‑oil supplement can make a noticeable difference in managing dry‑eye symptoms, thanks to the anti‑inflammatory power of EPA and DHA.
Prioritizing high purity, optimal omega‑3 ratios, and sustainable sourcing ensures you reap the ocular benefits while supporting overall health.
Pairing a quality supplement with proper hydration, a balanced diet, and regular eye‑care habits amplifies relief and promotes long‑term comfort.
By understanding how these nutrients interact with tear production and inflammation, you can confidently incorporate fish oil into your routine, helping to restore moisture, reduce irritation, and protect your eyes for the future.
