If you’ve ever wondered how to boost bone health, support cardiovascular function, and enhance immune resilience, the dynamic duo of Vitamin K2 and D3 may be your secret weapon.
Vitamin D3 helps your body absorb calcium, while Vitamin K2 ensures that calcium is directed to the bones and teeth—where it belongs—instead of accumulating in arteries and soft tissues.
Together, they work synergistically to promote stronger bones, a healthier heart, and balanced immune support.
However, with countless brands flooding the market, finding a supplement that delivers optimal absorption, clean ingredients, and real value can feel overwhelming.
Dosage levels vary widely, forms of K2 differ in effectiveness, and not all supplements are created with bioavailability in mind. That’s where we come in.
After carefully analyzing ingredient quality, K2 forms (MK-7 vs. MK-4), D3 potency, manufacturing standards, and customer feedback, we’ve done the heavy lifting for you.
In this guide, we reveal the 10 best Vitamin K2 + D3 supplements, hand-picked for potency, bioavailability, purity, and overall effectiveness—so you can confidently choose the right option for your health goals.
10. Nutricost Vitamin K2-MK7 + D3 120 Softgels
Vitamin K2 (MK‑7) and Vitamin D3 work together to support bone health, cardiovascular function, and immune resilience.
Each softgel delivers a potent 100 µg of the long‑acting MK‑7 form of K2 and a robust 5,000 IU of D3, giving you a full month’s supply in every bottle (120 softgels).
Formulated without gluten or genetically modified ingredients, these capsules are produced in a GMP‑compliant, FDA‑registered facility, ensuring purity and consistency you can trust.
Whether you’re looking to maintain strong bones, promote healthy calcium metabolism, or simply boost your overall wellness, Nutricost’s blend offers a convenient, high‑quality solution that fits easily into daily routines.
Pros
- High‑potency 100 µg MK‑7 per serving
- Powerful 5,000 IU D3 dose daily
- 120 softgels provide four‑month supply
- Gluten‑free, non‑GMO, clean formulation
- Made in GMP‑compliant, FDA‑registered plant
Cons
- May be unnecessary for those with sufficient sunlight
- Softgels can be large for some users
- Not suitable for individuals on anticoagulant therapy without doctor’s advice
9. Micro Ingredients D3 + K2 300 Softgels
Micro Ingredients Vitamin D3 + K2 MK‑7 delivers a powerful, once‑daily dose of sunshine‑derived nutrients in a convenient, easy‑to‑swallow softgel.
Each bottle contains 300 mini softgels, each packed with 5,000 IU of vitamin D3 and 100 µg of the highly bioavailable MK‑7 form of vitamin K2.
The two vitamins work synergistically: D3 supports calcium absorption while K2 directs calcium to bones and teeth, helping maintain strong skeletal health.
Formulated with non‑GMO, gluten‑free ingredients, the softgels are free from dairy, soy, tree nuts, preservatives, artificial colors, and flavors.
They’re third‑party lab tested for purity and safety, giving you confidence in every capsule. In warm weather the softgels may stick together—simply give the bottle a gentle shake or tap it on the counter to separate them, and the potency remains unchanged.
Pros
- High‑potency 5,000 IU vitamin D3 daily
- 100 µg MK‑7 vitamin K2 for optimal synergy
- Easy‑to‑swallow mini softgels, 300‑count supply
- Non‑GMO, gluten‑free, no common allergens
- Third‑party lab tested for purity and safety
Cons
- May clump in hot temperatures
- Requires daily, lifelong supplementation for best results
8. Bronson Vitamin K2 D3 (MK7) 60 Capsules
Bronson’s Vitamin K2 D3 (MK‑7) supplement delivers the synergistic duo that modern nutrition science says works best together.
Each capsule packs 5,000 IU (125 µg) of Vitamin D3 and 90 µg of the bio‑available K2‑MK7 form, ensuring that the calcium you absorb is directed straight to bone and teeth—not soft tissue.
The formula is non‑GMO, gluten‑free, soy‑free, and rigorously lab‑tested in Bronson’s New York facility, upholding the same high standards that have defined the brand since 1960.
Pharmacists who founded Bronson witnessed first‑hand how targeted supplementation can improve health, and today their legacy lives on in every easy‑to‑swallow capsule.
Key Features
– Vitamin D3 + K2‑MK7, the perfect pair
– Supports calcium absorption and bone distribution
– 5,000 IU D3 + 90 µg K2 per capsule
– NON‑GMO, gluten‑free, soy‑free, lab‑tested
– Trusted formulation dating back to 1960
Pros
- Maximizes vitamin D benefits with K2 synergy
- Promotes strong, healthy bone mineralization
- Easy‑to‑swallow capsules for daily use
- Clean label: non‑GMO, gluten‑ and soy‑free
- Backed by decades of pharmaceutical expertise
Cons
- May be high dose for vitamin D beginners
- Requires consistent daily intake for results
- Not suitable for those on blood‑thinners without doctor’s advice
7. Nature Made Vitamin D3 K2 Softgels
Nature Made’s Vitamin D3 + K2 softgels deliver a potent 5,000 IU (125 µg) of vitamin D in a convenient 30‑day supply.
Each softgel also provides 100 µg of vitamin K2, which works hand‑in‑hand with D3 to shepherd calcium straight to bone and teeth while keeping arteries clear.
Formulated for adults with higher vitamin D needs or a diagnosed deficiency, the daily softgel is gluten‑free, free of synthetic dyes and artificial flavors, and manufactured in the USA with globally sourced ingredients.
As the #1 pharmacist‑recommended vitamin brand, Nature Made offers a trustworthy, science‑backed solution for immune, bone, muscle, and overall healthy aging support—though the FDA has not evaluated these statements.
Pros
- High‑potency 5,000 IU vitamin D per softgel
- Adds 100 µg K2 for optimal calcium placement
- 30‑day supply simplifies daily routine
- Gluten‑free, no artificial colors or flavors
- Trusted #1 pharmacist‑recommended supplement brand
Cons
- May be too strong for low‑dose users
- Requires water for optimal absorption
- Not suitable for children without professional guidance
6. Bronson Vitamin K2 (MK7) with D3 Supplement 120 Capsules
Bronson Vitamin K2 (MK‑7) with D3 delivers a scientifically balanced duo that works together to support bone health and optimal calcium metabolism.
Each softgel packs 5,000 IU of Vitamin D3 and 90 µg of the highly bioavailable MK‑7 form of Vitamin K2, ensuring that the calcium you absorb is directed straight to your skeleton rather than soft tissues.
The formula is non‑GMO, gluten‑free, soy‑free, and undergoes rigorous laboratory testing in Bronson’s state‑of‑the‑art New York facility.
Rooted in a legacy that dates back to 1960, Bronson’s pharmacist‑driven expertise guarantees a trustworthy supplement that aligns with modern nutritional science.
Pros
- Synergistic K2 + D3 combo maximizes calcium benefits
- Supports strong, healthy bone density naturally
- Non‑GMO, gluten‑free, soy‑free capsules
- Lab‑tested for purity and potency every batch
- Trusted brand with over 60 years of experience
Cons
- May be pricey for budget shoppers
- Requires consistent daily intake for results
- Not suitable for those with vitamin K contraindications
5. Sports Research Vitamin D3 + K2
Sports Research® Vitamin D3 + K2 with coconut oil delivers a potent, plant‑based blend that works in harmony to keep your bones strong, your immune system ready, and calcium where it belongs.
Each softgel packs 5,000 IU of vegan D3 (derived from lichen) and 100 µg of MK‑7 K2 (fermented chickpeas), with MCT‑rich coconut oil to boost absorption.
The D3‑K2 duo supports calcium metabolism—D3 helps you absorb calcium, while K2 guides it straight to bone tissue, reducing the risk of unwanted arterial deposits.
Formulated for once‑daily use, the easy‑swallow softgels are free from soy, gluten, carrageenan, and artificial fillers. Certified Vegan, Non‑GMO Project Verified, and third‑party tested, every batch is manufactured in a cGMP‑compliant U.S. facility, ensuring purity and potency you can trust.
Pros
- Synergistic D3 + K2 bone support formula
- Vegan‑derived nutrients from lichen and chickpeas
- Coconut MCT oil enhances nutrient absorption
- One softgel daily, convenient dosing
- Clean, Non‑GMO, soy‑free certification
Cons
- May be pricey for larger households
- Softgel size could challenge some users
- Not suitable for those avoiding all animal‑derived supplements (contains lichen‑derived D3)
4. Dr. Berg Maximum Strength K2 D3
Dr. Berg Maximum Strength 2‑in‑1 Vitamin D3 K2 delivers a powerhouse blend of 10,000 IU of vitamin D3 and 100 µg of MK‑7 vitamin K2, paired with magnesium, vitamin B6, zinc, MCT oil and ox bile for optimal activation.
This 120‑capsule, 120‑day supply is formulated in a cGMP‑certified U.S. facility and undergoes four‑point lab testing to guarantee purity and potency.
The smart synergy of D3 + K2 plus essential cofactors ensures your body can absorb, activate, and use the nutrients efficiently, while the added MCT powder provides the healthy fat needed for superior bioavailability.
Backed by a 30‑day satisfaction guarantee, this high‑absorption formula is designed for anyone looking to support bone health, immune function, and cardiovascular wellness with a single, convenient daily capsule.
Pros
- High‑potency 10,000 IU vitamin D3 dose
- MK‑7 K2 enhances calcium metabolism
- Magnesium, B6, and zinc improve activation
- MCT oil boosts fat‑soluble vitamin absorption
- Lab‑tested, cGMP‑certified U.S. manufacturing
Cons
- Requires dietary fat for best results
- May be too strong for vitamin‑D beginners
- Ox bile could irritate sensitive stomachs
3. Dr. Berg D3 K2 5000 IU
Dr. Berg’s Maximum Strength 2‑in‑1 Vitamin D3 + K2 delivers a potent 5,000 IU of naturally derived vitamin D3 paired with 50 µg of MK‑7 vitamin K2.
Each capsule also packs a synergistic blend of magnesium, vitamin B6, zinc, MCT oil, and ox bile—ingredients that help your body absorb, activate, and efficiently use the fat‑soluble vitamins.
The MCT powder provides a healthy fat source, boosting bioavailability so you get the most out of every dose. Formulated in the USA in cGMP‑certified facilities, each batch undergoes four‑point lab testing for purity, potency, and consistency.
With a 60‑day supply, this supplement is designed for anyone looking to support bone health, immune function, and cardiovascular wellness. And if you’re not satisfied within 30 days, the company will make it right.
Pros
- High‑potency 5,000 IU D3 per capsule
- MK‑7 K2 enhances calcium metabolism
- Magnesium, B6, and zinc improve absorption
- MCT oil boosts fat‑soluble vitamin uptake
- 30‑day satisfaction guarantee
Cons
- Requires fat intake for optimal absorption
- Capsules may be large for some users
- Only a 60‑day supply per bottle
2. Micro Ingredients D3 + K2 300 Softgels
Micro Ingredients’ 2‑in‑1 Vitamin D3 + K2 softgels deliver a powerhouse dose of sunshine vitamin synergy in a convenient, ultra‑small capsule.
Each of the 300 mini softgels is infused with virgin coconut MCT oil, the ideal fat carrier that boosts absorption of the fat‑soluble vitamins.
One softgel supplies 10,000 IU of vitamin D3 (cholecalciferol) and 200 µg of vitamin K2 (MK‑7), the premium, long‑acting form of K2 that works hand‑in‑hand with D3 to support bone health, cardiovascular function, and immune resilience.
The formula is non‑GMO, gluten‑free, and free from soy and dairy, and every batch undergoes third‑party lab testing for purity, potency, and safety.
These extra‑strength softgels are easy to swallow, making daily compliance a breeze. While the product is not evaluated by the FDA and isn’t intended to diagnose, treat, cure, or prevent disease, it offers a clean, high‑quality way to fill two essential micronutrient gaps with one daily dose.
Pros
- Double‑strength D3 + K2 for maximal support
- MCT coconut oil enhances nutrient absorption
- Mini softgels are easy to swallow daily
- Non‑GMO, gluten‑free, soy‑ and dairy‑free formula
- Third‑party tested for purity and potency
Cons
- High dose may not suit all individuals
- Requires consistent daily intake for benefits
- Not suitable for vegans due to gelatin capsule
1. Pure Encapsulations Vitamin D3 & K2 120 Capsules
Pure Encapsulations Vitamin D3 & K2 delivers a clinically‑backed blend that works on three fronts—bone strength, vascular health, and immune resilience.
Each capsule provides 4,000 IU of vitamin D3 paired with vitamin K2, a synergy that encourages optimal calcium absorption while directing calcium away from arteries and into bone tissue.
The formula is crafted from premium, non‑GMO ingredients and undergoes rigorous testing for purity, so you get a product free from gluten, common allergens, artificial additives, and unnecessary fillers.
Whether you’re looking to maintain skeletal integrity, support flexible blood vessels, or boost seasonal immunity, this capsule offers a clean, science‑driven solution you can trust.
Pros
- Supports strong, healthy bones daily
- Promotes arterial flexibility and calcium balance
- Boosts immune function during seasonal changes
- Gluten‑free, non‑GMO, allergen‑free formula
- Manufactured with rigorous purity testing
Cons
- Gelatin capsule may not suit vegans
- May require higher dose for severe deficiency
- Not a substitute for prescription vitamin therapy
Frequently Asked Questions
What makes a Vitamin K2 + D3 supplement “the best” for optimal health?
- High‑quality forms – Look for MK‑7 (a long‑acting form of K2) and cholecalciferol (D3), which are the most bioavailable.
- Balanced ratio – A 100 µg K2 : 5,000 IU D3 ratio is commonly recommended to support calcium metabolism without excess.
- Clean ingredients – Choose a product that’s non‑GMO, gluten‑free, and free of unnecessary fillers, artificial colors, or allergens.
- Third‑party tested – Certifications from NSF, USP, or ConsumerLab ensure potency and purity.
How should I take a Vitamin K2 + D3 supplement for maximum absorption?
- Take with a meal containing fat – Both K2 and D3 are fat‑soluble, so a small amount of healthy fat (e.g., avocado, nuts, olive oil) boosts uptake.
- Consistent timing – Daily intake at the same time (morning or dinner) helps maintain steady blood levels.
- Avoid high doses of calcium or iron at the same moment – Large amounts can compete for absorption; spacing them by a few hours is ideal.
Typical dosage: 100 µg MK‑7 + 5,000 IU D3 once daily, but follow the label or your healthcare provider’s guidance.
Conclusion
Choosing the right Vitamin K2 + D3 supplement ultimately comes down to balancing potency, purity, and formulation that aligns with your health goals.
Prioritize products that source high‑quality, bioavailable forms of both nutrients, provide transparent third‑party testing, and avoid unnecessary additives.
Remember that consistency is key; a well‑designed supplement can help support bone density, cardiovascular health, and immune function when taken daily alongside a balanced diet.
By understanding these core criteria, you can confidently select a supplement that delivers the synergistic benefits of K2 and D3, empowering you to maintain optimal wellness throughout the year.
