Maintaining a healthy digestive system is essential for overall well-being, and DGL supplements can play a key role in supporting gut health. DGL, or deglycyrrhizinated licorice, is known for its natural soothing properties that help relieve occasional heartburn, indigestion, and stomach discomfort.
These supplements work by promoting a balanced digestive environment, supporting the lining of the stomach, and reducing inflammation. With many options available on the market, choosing the right DGL supplement can be overwhelming.
This guide highlights the top 10 best DGL supplements, making it easier to find a product that promotes digestive comfort and overall gastrointestinal health.
10. Pure Encapsulations DGL Plus – Gut Health Supplements
Pure Encapsulations DGL Plus is a science‑backed, vegan formula that targets the entire gastrointestinal tract. Each capsule delivers a synergistic blend of deglycyrrhizinated licorice (DGL), aloe vera extract, marshmallow root, and slippery elm bark—herbs traditionally known to soothe and protect the stomach lining.
The non‑GMO, gluten‑free composition makes it suitable for men and women seeking clean, allergen‑free digestive support. As a dietary supplement, simply take one capsule daily before a meal, or follow the guidance of a health professional.
Pure Encapsulations’ “Pure Difference” philosophy means the product is free from common allergens, artificial additives, and unnecessary fillers, allowing you to focus on gut health without compromise.
Pros
- Supports healthy stomach lining and GI tract*
- Combines DGL with aloe, marshmallow, elm
- Vegan, gluten‑free, non‑GMO ingredients
- Free from common allergens & artificial additives
- Simple once‑daily dosing before meals
Cons
- May be pricey compared to generic brands
- Requires consistent daily use for best results
- Not intended for children without professional advice
9. Carlyle DGL Deglycyrrhizinated Licorice Capsules
Carlyle’s DGL Deglycyrrhizinated Licorice Capsules deliver the time‑honored benefits of Chinese licorice in a modern, vegetarian format.
Each serving packs 4,000 mg of licorice‑equivalent plant compounds, carefully stripped of glycyrrhizin to avoid the typical side‑effects while preserving the soothing power of the root.
The capsules are gluten‑free, wheat‑free, yeast‑free, lactose‑free, soy‑free, and non‑GMO, so they fit easily into most dietary plans. Every batch undergoes rigorous laboratory testing, ensuring that only pure, trusted ingredients reach your bottle—Carlyle’s hallmark of superior quality and a 100 % satisfaction guarantee.
Whether you’re supporting digestive comfort, oral health, or overall wellness, these capsules offer a clean, honest supplement that aligns with a health‑first lifestyle.
Pros
- Powerful plant compounds from traditional DGL licorice
- Vegetarian capsules with 4,000 mg licorice equivalent
- Free from gluten, wheat, soy, and lactose
- Laboratory‑tested for purity and potency
- Non‑GMO, no artificial flavors or preservatives
Cons
- May be pricey compared to generic brands
- Requires multiple capsules per serving
- Not suitable for those avoiding all herbal supplements
8. NusaPure DGL 500 mg, 200 Capsules
NusaPure DGL Licorice Extract delivers a potent 500 mg dose of deglycyrrhizinated licorice in every veggie capsule, offering a convenient, plant‑based solution for digestive comfort.
With 200 capsules in each bottle, you get a full 200‑day supply—perfect for long‑term wellness routines without the hassle of frequent re‑ordering. Each capsule is vegan, non‑GMO, and free from animal‑derived ingredients, making it suitable for a wide range of dietary preferences.
The formula is crafted with care, using high‑quality ingredients that meet strict cGMP standards in a registered manufacturing facility, ensuring purity and consistency you can trust.
Pros
- 500 mg DGL licorice per capsule, potent support
- 200‑day supply eliminates frequent repurchasing
- Vegan, vegetarian, and non‑GMO formulation
- Manufactured in a cGMP‑registered facility
- Quality‑focused ingredients for reliable results
Cons
- May be pricey for budget shoppers
- Requires daily intake for full benefits
- Not suitable for those allergic to licorice
7. Swanson DGL 750mg
Swanson High Potency DGL (Deglycyrrhizinated Licorice) capsules deliver a concentrated, gut‑friendly formula designed to soothe the stomach and support overall digestive health.
Each softgel packs 750 mg of premium licorice root extract that has been carefully processed to contain less than 3 % glycyrrhizinic acid, so you can enjoy the benefits without the typical side‑effects.
Taken with a glass of water before meals, the capsules help maintain a healthy gastrointestinal lining, reduce occasional heartburn, and promote regularity.
Made in Swanson’s GMP‑certified facilities, every batch undergoes rigorous purity and potency testing by independent third‑party labs, ensuring you receive a product that lives up to its “science‑backed” promise. With a 24‑month shelf life, these capsules are a convenient, long‑lasting addition to your daily wellness routine.
Pros
- Twice the potency of regular DGL tablets
- Low glycyrrhizinic acid for safe daily use
- Supports stomach lining and GI comfort
- Simple once‑daily dosage before meals
- GMP‑certified with third‑party testing
Cons
- May not suit those avoiding all licorice
- Requires water to swallow each capsule
- Not a substitute for medical treatment
6. Nutricost DGL Capsules
Nutricost’s DGL Deglycyrrhizinated Licorice Extract Capsules deliver a powerful 5,000 mg equivalent dose of licorice per serving, providing the concentrated benefits of this traditional herb without the glycyrrhizin that can cause unwanted side effects.
Each bottle contains 120 vegan, non‑GMO capsules, giving you a full four‑month supply to support digestive comfort, gastric health, and overall wellness. The product is manufactured in an NSF‑certified GMP‑compliant facility, ensuring strict adherence to quality and safety standards.
Every batch undergoes rigorous third‑party testing by ISO‑accredited laboratories, confirming potency, purity, and consistency. Nutricost’s commitment to transparency means you receive a reliably tested supplement you can trust for daily use.
Pros
- High‑potency 5,000 mg licorice equivalent dose
- 120‑day supply supports long‑term wellness
- NSF‑certified GMP facility ensures safety
- Independent ISO‑accredited testing confirms purity
- Vegan, non‑GMO formula fits dietary needs
Cons
- Capsules may be large for some
- Not intended for pregnant individuals
- May interact with certain medications
5. Nature’s Bounty DGL Licorice 60 Servings
Liposomal DGL Licorice Root Extract blends a full spectrum of plant‑based ingredients—Deglycyrrhizinated Licorice (DGL), L‑Glutamine, Marshmallow Root, Aloe Vera, Clove Bud, Slippery Elm Bark, and a hint of Capsicum Fruit—into a single liquid formula.
By removing glycyrrhizin, DGL offers the historic soothing benefits of licorice without the blood‑pressure concerns, making it safe for daily use. The liposomal encapsulation protects each active compound and delivers it sublingually, so absorption occurs in under a minute, far faster than chewable tablets or capsules.
Each 2 ml serving provides roughly four drops, and a 250‑drop bottle supplies 60 convenient servings. The dropper design fits easily into a pocket or bag, letting you support stomach lining health, balance digestion, and enjoy everyday gut comfort wherever you are.
Pros
- Rapid sublingual absorption under one minute
- Complete plant‑based blend for holistic gut support
- Gentle DGL formulation safe for daily use
- Convenient liquid drops eliminate chewing hassles
- 60‑serving bottle perfect for travel and busy schedules
Cons
- Liquid format may not suit those preferring pills
- Requires sublingual hold for optimal absorption
- Taste may be strong for sensitive palates
4. Zazzee DGL 20X 120 Capsules
Zazzee USDA Organic DGL Licorice delivers an extra‑strong 7,000 mg dose per vegan capsule, thanks to a potent 20:1 deglycyrrhizinated extract.
Each bottle contains 120 capsules, providing a full four‑month supply—far more than competing brands that require two capsules per serving and offer fewer pills.
Certified organic by the USDA, every ingredient—from the stabilizers to the capsule shell—is 100 % vegan, non‑GMO, and free of allergens such as gluten, soy, dairy, and nuts.
The formulation contains no sweeteners, artificial flavors, or filler chemicals, ensuring you receive only pure, natural support for digestive health. Produced in a U.S. GMP‑certified facility, Zazzee follows rigorous quality‑control standards, so you can trust the safety and potency of each dose.
Whether you’re looking to soothe occasional stomach discomfort or maintain overall gut balance, this all‑natural, high‑potency DGL licorice offers unparalleled value and peace of mind.
Pros
- 7,000 mg strength per capsule (20:1 extract)
- Four‑month supply in a single bottle
- USDA‑certified organic, non‑GMO ingredients
- Fully vegan formula, allergen‑free
- Made in USA under strict GMP standards
Cons
- May be pricier than non‑organic alternatives
- Requires consistent daily intake for best results
- Not intended for use by pregnant or nursing individuals without medical advice
3. Pure Encapsulations DGL Plus
Pure Encapsulations DGL Plus is a premium gut‑health supplement designed for both men and women. Each vegan capsule blends deglycyrrhizinated licorice (DGL) with soothing herbal extracts—marshmallow root, aloe vera, and slippery elm bark—to support a healthy stomach lining and gastrointestinal tract.
The formula is non‑GMO, gluten‑free, and free from common allergens, artificial colors, and unnecessary fillers, making it a clean choice for daily digestive wellness.
For optimal benefit, take one capsule before a meal, or follow the guidance of a health professional. Whether you’re looking to maintain regular digestion or give extra care to a sensitive gut, DGL Plus delivers clinically‑backed botanicals in a convenient, vegan capsule.
Pros
- Supports healthy stomach lining and GI tract*
- Combines DGL with aloe vera, marshmallow, elm
- Vegan, gluten‑free, and non‑GMO formulation
- Free from common allergens and artificial additives
- Simple once‑daily dosage before meals
Cons
- May be pricey compared to generic brands
- Requires consistent daily use for results
- Not intended for pregnant or nursing women without professional advice
2. Natural Factors DGL Chewable Tablets
Natural Factors DGL Chewable delivers a gentle, plant‑based boost for your digestive system. Each chewable tablet packs a concentrated dose of deglycyrrhizinated licorice root extract, a time‑tested remedy known for soothing the stomach and supporting healthy gut function.
By strengthening the natural mucus lining of both the stomach and intestinal wall, the formula helps guard against irritation and promotes a more resilient digestive tract.
The extract is carefully processed to remove glycyrrhizin, eliminating the risk of blood‑pressure spikes while preserving the soothing benefits of licorice. With 90 chewable tablets (90 servings), you get a convenient, non‑GMO, gluten‑free supplement that’s easy to incorporate into any daily routine—just chew and go.
Whether you’re looking to ease occasional heartburn, support overall gut health, or simply give your stomach lining a protective edge, Natural Factors DGL Chewable offers a clean, effective solution backed by botanical tradition.
Pros
- Supports natural mucus lining integrity
- Stimulates protective factors for gut health
- Glycyrrhizin‑free to avoid blood‑pressure concerns
- Convenient chewable format, no water needed
- Non‑GMO and gluten‑free formulation
Cons
- May require several weeks for full effect
- Not a substitute for prescribed medication
- Chewy texture may not suit all preferences
1. Natural Factors DGL Chewable Tablets
Natural Factors DGL Chewable delivers a gentle, plant‑based boost for digestive comfort. Each tablet combines deglycyrrhizinated licorice (DGL) extract with a clean, vegan formula that’s free from dairy, gluten, soy, and common allergens.
Designed to protect the mucosal lining of the stomach and intestinal wall, the chewable tablets are easy to take—simply chew 1 tablet 1‑3 times daily, 20 minutes before meals, or as advised by a health professional.
The supplement is non‑GMO, gluten‑free, and manufactured under the direct oversight of Natural Factors, a family‑owned B‑Corp that operates carbon‑neutral facilities and employs third‑party testing at every production stage to guarantee purity and potency.
With 180 chewable tablets (180 servings), you get three months of support for gut health without compromising your dietary preferences.
Pros
- Supports stomach lining integrity naturally
- Chewable tablets for hassle‑free dosing
- Vegan, non‑GMO, gluten‑free formulation
- Backed by B‑Corp, carbon‑neutral standards
- Third‑party tested for purity and safety
Cons
- May have a mild licorice aftertaste
- Not ideal for those with hypertension concerns
- Requires consistent pre‑meal timing for best results
Frequently Asked Questions
What is DGL and how does it differ from regular licorice root?
DGL (Deglycyrrhizinated Licorice) is a form of licorice root that has had the compound glycyrrhizin removed. Glycyrrhizin can cause side effects such as high blood pressure, water retention, and potassium loss when taken in large amounts.
By removing it, DGL retains the soothing, anti‑inflammatory properties of licorice—particularly the flavonoids and mucilage that help protect the stomach lining—while minimizing those risks. This makes DGL a safer, long‑term option for digestive support.
How do I choose the best DGL supplement for gut health?
- Form: Chewable tablets, capsules, or powdered extracts are common. Chewables are often preferred because the act of chewing releases the mucilage directly in the mouth, which can aid digestion.
- Dosage: Look for products that provide 380–500 mg per serving, the typical dose used in clinical studies.
- Purity: Choose a supplement that is non‑GMO, gluten‑free, and free of artificial additives. Third‑party testing (USP, NSF, or ConsumerLab) adds an extra layer of confidence.
- Brand reputation: Established brands with good customer reviews and transparent sourcing tend to be more reliable.
Conclusion
Choosing the right DGL supplement ultimately hinges on balancing potency, purity, and personal tolerance, while keeping an eye on added ingredients that support digestive health.
Prioritizing products that are clinically validated, free from unnecessary fillers, and manufactured under strict quality standards can help you reap the soothing benefits of deglycyrrhizinated licorice without unwanted side effects.
Remember that consistency, proper dosage, and pairing the supplement with a balanced diet and lifestyle are just as critical as the supplement itself. By staying informed and listening to your body’s response, you can confidently integrate DGL into your routine for lasting gastrointestinal comfort.
