Fish oil supplements rich in omega-3 fatty acids EPA and DHA are widely used to support heart, brain, eye, and joint health. As research continues to highlight the benefits of these essential fats, many people choose supplements to help fill nutritional gaps.
With so many options available, it can be hard to know which products deliver quality, purity, and effective doses. This guide reviews the top 10 best fish oil supplements for omega-3, offering ratings based on potency, sourcing, formulation, and value.
Whether you are new to supplements or looking to upgrade your routine, these reviews will help you make an informed choice.
10. Nature Made Omega-3 Fish Oil Minis
Nature Made Extra Strength Burp‑Less Fish Oil delivers a potent 1,400 mg dose of omega‑3s in easy‑to‑swallow minis. Each 30‑day supply (60 softgels) provides 680 mg EPA and 250 mg DHA per serving, nutrients that support heart rhythm, cognitive function, and visual health.
The softgels are purified to remove mercury and formulated to minimize the dreaded “fishy burp,” making daily compliance a breeze. With no added colors, milk, or shellfish ingredients, they’re gluten‑free and suitable for most dietary restrictions.
The brand is the #1 pharmacist‑recommended vitamin and supplement line, underscoring its reputation for quality and safety. For optimal absorption, simply take two softgels with water and a meal.
Whether you’re looking to protect cardiovascular health, sharpen mental focus, or maintain eye clarity, these mini softgels offer a convenient, high‑potency solution.
Pros
- Supports heart, brain & eye health†
- Easier to swallow mini softgels
- Burp-less formula reduces aftertaste
- Gluten free with no color added
- Trusted pharmacist-recommended brand
Cons
- Higher-strength may be more costly
- Not suitable for those allergic to fish
- Needs daily consistency for best results
9. Focus Relief Plus Omega 3 Fish Oil
Focus Relief Plus Dry Eye Formula delivers a potent blend of omega‑3 fatty acids designed to nurture healthy tears and support retinal function.
Each serving provides 1,620 mg of re‑esterified triglyceride (rTG) fish oil, with over 90 % EPA and DHA, plus 75 mg of GLA for added anti‑inflammatory benefits.
Developed and recommended by eye doctors, the supplement targets occasional dry‑eye symptoms and promotes overall ocular health. The soft‑gel capsules are easy to swallow and are intended to be taken three times daily with a meal.
Produced in the USA at an NSF‑certified facility, every batch undergoes third‑party certification of analysis, ensuring purity and consistency for every consumer.
Pros
- Clinically‑backed formula supports dry‑eye relief
- High‑concentration rTG omega‑3 (>90 % EPA/DHA)
- Includes GLA for extra anti‑inflammatory effect
- Easy‑to‑swallow softgels, three‑a‑day dosing
- NSF‑certified, third‑party tested for safety
Cons
- Requires daily intake with meals
- Not suitable for vegans (fish‑derived)
- May cause mild fish‑oil aftertaste for some
This 180‑count, 60‑day supply offers a convenient, doctor‑developed solution for anyone looking to protect their eyes and keep tear production at its best.
8. MegaRed Ultra 1000mg Omega-3 Krill Oil
MegaRed Ultra Strength 1000 mg Omega‑3 Krill Oil delivers a powerhouse blend of EPA, DHA, astaxanthin, and phospholipids in a single, easy‑to‑swallow softgel.
Sourced exclusively from the abundant Antarctic krill, the formula provides a sustainable, high‑purity source of omega‑3s that’s been shown to raise the Omega‑3 Index and support cardiovascular, brain, joint, and eye health.
Because the oil is bound to phospholipids, it’s absorbed more efficiently than traditional fish oil and leaves no fishy aftertaste or odor.
Each ultra‑concentrated softgel packs the equivalent of two standard 500 mg krill oil capsules, giving you double the omega‑3 benefits in half the pills.
Doctor‑recommended and free of artificial fillers, MegaRed is a convenient, once‑daily solution for anyone looking to boost heart health and overall wellness without the unpleasant fish‑oil flavor.
Pros
- Doctor‑recommended brand for heart health
- Sustainable Antarctic krill source ensures purity
- Phospholipid delivery for superior absorption
- No fishy aftertaste or odor
- Two‑times the omega‑3 in one softgel
Cons
- Higher price than standard fish oil
- Not suitable for shellfish allergy sufferers
- Requires daily consistency for best results
7. Nature Made Omega-3 Fish Oil, 2800mg, 60 Softgels
Nature Made Extra Strength Omega‑3 delivers a potent 2,800 mg of fish‑oil‑derived EPA & DHA per serving, packaged in 60 easy‑to‑swallow softgels for a full 30‑day supply.
Each dose provides 2,000 mg of essential Omega‑3 fatty acids (1,366 mg EPA, 504 mg DHA) to support a healthy heart, sharp brain function, clear vision, and balanced mood.
The “Burp‑Less” formula is triple‑filtered to remove mercury and other contaminants, ensuring a pure, high‑quality product.
These softgels are gluten‑free, contain no added colors, milk, or shellfish, and are recommended by pharmacists as a trusted daily supplement. For optimal absorption, simply take two softgels with water and a meal.
Pros
- High‑potency 2,800 mg fish‑oil dose
- Supports heart, brain, eyes, and mood
- Burp‑Less, mercury‑free, triple‑filtered formula
- Gluten‑free, no color, milk, or shellfish
- Pharmacist‑recommended, trusted brand
Cons
- Requires two softgels daily
- Not suitable for vegans (fish source)
- May cause mild fish aftertaste for some
6. Nordic Naturals Nordic Omega-3 Fish Oil Capsules
Designed for daily eye‑care, this triglyceride‑based fish oil blend delivers a potent mix of 515 mg EPA, 415 mg DHA, 40 mg Omega‑7, plus Vitamin E, Vitamin C, Vitamin B‑6 and Magnesium.
The synergistic formula works from the inside out to nourish the retina, support clear vision, and protect delicate ocular tissues. Unlike many pricey alternatives, the softgels are burpless and easy to swallow—no fishy aftertaste, no uncomfortable belches.
Each capsule is crafted with pure triglyceride omega‑3s for optimal absorption, making it a convenient addition to any wellness routine.
With every purchase, a portion of the profits goes toward eye‑care assistance for those in need, and the product is backed by a 100 % satisfaction guarantee.
Pros
- Burpless softgels, no fishy aftertaste
- High EPA & DHA concentrations for retina health
- Includes Omega‑7 and essential vitamins
- Easy‑to‑swallow capsules fit daily routines
- Supports overall eye comfort and visual clarity
Cons
- Requires consistent daily intake for results
- May not suit vegans or vegetarians
- Slightly higher price than basic fish oils
5. Focus Relief Plus Dry Eye Formula (270 ct)
A powerful blend of re‑esterified triglyceride (rTG) omega‑3s, Focus Relief Plus delivers 1,620 mg of fish oil per serving—over 90 % EPA and DHA—to help maintain healthy tear production and support retinal health.
Developed and recommended by eye doctors, the formula also includes 75 mg of gamma‑linolenic acid (GLA) for added ocular comfort. The soft‑gel capsules are easy to swallow and are meant to be taken three times daily with a meal, providing a convenient 90‑day supply (270 ct).
Produced in an NSF‑certified U.S. facility, each batch undergoes third‑party testing to guarantee purity and potency, putting patient safety first.
Pros
- Clinically‑backed omega‑3 concentration supports tear health
- High EPA/DHA levels exceed most leading supplements
- Includes GLA for extra ocular inflammation relief
- Doctor‑developed formula targets dry‑eye and retina
- Easy‑swallow softgels simplify daily dosing
Cons
- Requires three softgels per day
- May cause mild fish‑oil aftertaste
- Not suitable for vegans or vegetarians
4. Nature Made Omega-3 Fish Oil Supplements
Nature Made Burp‑Less Ultra Omega‑3 delivers a potent 1,400 mg dose of fish‑oil softgels in a convenient once‑daily format. Each softgel is refined to remove mercury and formulated with a special coating that minimizes the dreaded “fishy burp,” making it easy to stay consistent.
With 683 mg EPA and 252 mg DHA per serving, this supplement supports cardiovascular health, cognitive function, and visual acuity.
The 90‑softgel bottle provides a full three‑month supply, and the formula is gluten‑free, dairy‑free, and free from added colors or shellfish—ideal for a variety of dietary preferences.
For best results, take the softgel with water and a meal to enhance absorption. As a #1 pharmacist‑recommended brand, Nature Made offers confidence in quality and purity, though the statements have not been evaluated by the FDA.
Pros
- One‑a‑day convenience for 90‑day supply
- Mercury‑purified fish oil eliminates heavy‑metal concerns
- Burp‑less coating prevents unpleasant aftertaste
- High EPA/DHA levels support heart, brain, eyes
- Gluten‑free, dairy‑free, no artificial colors
Cons
- Not suitable for vegans or vegetarians
- Requires water and food for optimal absorption
- FDA disclaimer limits health claim verification
3. Macuhealth Omega 3 Fish Oil, 120 Softgels
Macuhealth Omega 3 Fish Oil delivers a powerhouse blend of marine‑derived nutrients designed to support eye and brain health.
Each serving packs 1,100 mg DHA and 1,100 mg EPA, plus an extra 250 mg of complementary omega‑3 fatty acids, giving you a total of 2,200 mg of omega‑3s in a single, easy‑to‑swallow softgel.
The formula uses high‑purity fish oil enriched with rosemary extract, sunflower oil, and natural tocopherols to protect against oxidation and preserve freshness. Softgels are coated to minimize aftertaste, making daily supplementation pleasant.
With flexible dosing guidelines, you can tailor the intake to match your personal health goals, whether you’re looking for a maintenance boost or a more intensive regimen.
Pros
- Triple‑strength DHA and EPA for brain support
- 2,200 mg total omega‑3s per serving
- Smooth‑coated softgels reduce fishy aftertaste
- Premium fish oil combined with antioxidant blend
- Adjustable dosing fits individual health needs
Cons
- Higher price point than standard fish oils
- Requires two softgels per daily dose
- Not suitable for vegans or vegetarians
2. TheraTears Omega 3 Supplement, 1200mg
TheraTears Omega 3 Supplement for Eye Care delivers a powerful blend of 1200 mg fish oil, organic flaxseed oil, and vitamin E to nurture ocular health.
Each serving supplies 450 mg EPA, 300 mg DHA, and 450 mg ALA—essential fatty acids that support tear‑film stability, reduce dryness, and promote overall eye comfort.
The formula is built on 18 years of ophthalmology research and has been clinically tested, giving you confidence that the nutrients are both safe and effective.
As a doctor‑recommended brand (per the ProVoice Survey, 9/1/23‑8/31/24), TheraTears is also often eligible for FSA/HSA reimbursement, making premium eye care more affordable.
Whether you spend long hours in front of screens or simply want to maintain healthy vision, this supplement offers a convenient, daily boost to keep your eyes hydrated and resilient.
Pros
- Clinically tested triglyceride fish oil blend
- High EPA, DHA, and ALA content per dose
- Ophthalmologist‑created after 18 years of research
- Doctor‑recommended brand with strong survey backing
- Potential FSA/HSA eligibility for cost savings
Cons
- May cause mild fishy aftertaste for some
- Not suitable for those with severe fish oil allergies
- Requires daily intake for full benefits
1. Nature’s Bounty Dry Sense Omega 3
Focus Relief Plus Formula for Dry Eyes delivers a potent, doctor‑developed blend of omega‑3s designed to nurture healthy tears and support retinal health.
Each serving packs 1,620 mg of re‑esterified triglyceride (rTG) fish oil, providing over 90 % EPA and DHA—a higher concentration than most eye supplements on the market. The formula also includes 75 mg of gamma‑linolenic acid (GLA) to further promote ocular comfort.
Developed and recommended by eye doctors, this supplement is manufactured in an NSF‑certified U.S. facility, with every batch undergoing third‑party certification of analysis for purity and potency.
The soft‑gel capsules are easy to swallow; just three per day with a meal can help alleviate occasional dryness and support overall retinal function.
Pros
- Doctor‑developed, eye‑care specific formula
- High‑concentration rTG omega‑3s (90 % EPA/DHA)
- Includes GLA for added ocular support
- NSF‑certified U.S. manufacturing standards
- Easy‑to‑swallow softgels, three daily
Cons
- Requires daily dosing with meals
- Not a substitute for prescription eye drops
- May cause mild fishy aftertaste for sensitive users
Frequently Asked Questions
What makes a fish oil supplement effective for dry‑eye relief?
- High EPA/DHA concentration – EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) are the omega‑3s most linked to tear‑film stability. Look for ≥ 500 mg EPA + DHA per serving.
- Triglyceride or re‑esterified form – These forms are better absorbed than ethyl‑ester oils, delivering more omega‑3s to the ocular surface.
- Purity & freshness – Certified molecular‑distillation removes mercury, PCBs, and other contaminants; a low oxidation (PV < 5 meq O₂/kg) label indicates freshness.
- Added antioxidants – Vitamin E or astaxanthin helps prevent oxidation of the oil, preserving potency.
Which fish‑oil brands are most recommended for dry eyes?
| Brand | EPA/DHA per 1 g | Form | Purity Certification | Notable Extras |
|---|---|---|---|---|
| Nordic Naturals Ultimate Omega | 650 mg EPA + 450 mg DHA | Triglyceride | IFOS 6-Star, GOED GMP | Added vitamin E |
| Viva Naturals Omega-3 | 500 mg EPA + 300 mg DHA | Re-esterified triglyceride | IFOS 5-Star | No artificial flavors |
| Sports Research Triple-Strength Omega-3 | 800 mg EPA + 600 mg DHA | Triglyceride | IFOS Certified, cGMP | Wild-caught fish oil, non-GMO |
Tip: For dry-eye support, consistency matters. Most studies suggest benefits after 6–8 weeks of daily use, especially when combined with proper hydration and reduced screen strain.
Conclusion
Choosing the right fish oil can be a game‑changer for anyone struggling with dry‑eye discomfort, as the omega‑3s help lubricate the ocular surface, reduce inflammation, and support overall tear‑film stability.
Prioritizing high‑quality, sustainably sourced oils with adequate EPA and DHA levels, minimal oxidation, and transparent third‑party testing ensures you reap the full therapeutic benefits while safeguarding your health.
Pairing a consistent supplement regimen with proper hydration, a balanced diet, and regular eye‑care habits maximizes relief and may even lessen dependence on artificial tears.
With thoughtful selection and consistent use, fish oil can become a reliable ally in maintaining comfortable, healthy eyes.
